KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNB1
All Species:
31.21
Human Site:
T685
Identified Species:
52.82
UniProt:
P35222
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35222
NP_001091679.1
781
85497
T685
L
T
S
S
L
F
R
T
E
P
M
A
W
N
E
Chimpanzee
Pan troglodytes
XP_001137676
774
84747
T678
L
T
S
S
L
F
R
T
E
P
M
A
W
N
E
Rhesus Macaque
Macaca mulatta
XP_001115474
511
55731
G434
G
L
D
I
G
A
Q
G
E
P
L
G
Y
R
Q
Dog
Lupus familis
XP_850439
744
81740
D658
I
S
E
D
K
N
P
D
Y
R
K
R
V
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q02248
781
85452
T685
L
T
S
S
L
F
R
T
E
P
M
A
W
N
E
Rat
Rattus norvegicus
Q9WU82
781
85436
T685
L
T
S
S
L
F
R
T
E
P
M
A
W
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516985
781
85506
T685
L
T
S
S
L
F
R
T
E
P
M
A
W
N
E
Chicken
Gallus gallus
NP_990412
781
85420
T685
L
T
S
S
L
F
R
T
E
P
M
A
W
N
E
Frog
Xenopus laevis
P26233
781
85431
T685
L
T
S
S
L
F
R
T
E
P
M
P
W
N
E
Zebra Danio
Brachydanio rerio
NP_571134
780
85502
T684
L
T
S
S
L
F
R
T
E
P
M
T
W
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18824
843
91134
E698
L
T
N
S
L
L
R
E
D
N
N
I
W
A
N
Honey Bee
Apis mellifera
XP_391947
811
88602
E701
L
T
N
S
L
L
R
E
D
T
N
L
W
N
N
Nematode Worm
Caenorhab. elegans
O44326
678
74493
N601
K
S
V
V
T
Y
A
N
G
V
L
S
N
L
K
Sea Urchin
Strong. purpuratus
NP_001027543
825
89711
G709
L
G
N
S
L
F
R
G
D
S
V
P
W
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
65.4
66.4
N.A.
99.8
99.7
N.A.
99.7
99.3
97.4
97.1
N.A.
65.7
67.6
28.5
67.2
Protein Similarity:
100
99
65.4
77.4
N.A.
99.8
99.7
N.A.
99.8
99.6
99
98.9
N.A.
77.2
80.1
46.4
77.7
P-Site Identity:
100
100
13.3
0
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
40
46.6
0
40
P-Site Similarity:
100
100
40
20
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
53.3
60
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
0
0
0
43
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
8
22
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
0
0
0
15
65
0
0
0
0
0
58
% E
% Phe:
0
0
0
0
0
65
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
8
0
0
15
8
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% K
% Leu:
79
8
0
0
79
15
0
0
0
0
15
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
58
0
0
0
0
% M
% Asn:
0
0
22
0
0
8
0
8
0
8
15
0
8
65
15
% N
% Pro:
0
0
0
0
0
0
8
0
0
65
0
15
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
79
0
0
8
0
8
0
8
0
% R
% Ser:
0
15
58
79
0
0
0
0
0
8
0
8
0
8
0
% S
% Thr:
0
72
0
0
8
0
0
58
0
8
0
8
0
0
0
% T
% Val:
0
0
8
8
0
0
0
0
0
8
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
79
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _